Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives
Regioselective Dieckmann cyclisations using an N-acyloxazolidine derived from L-serine give substituted tetramic acids in high yield and enantioselectivity. The products are easily deprotected under mild conditions to give hydroxymethyltetramic acids.
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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| _version_ | 1797064461916307456 |
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| author | Andrews, MD Brewster, A Crapnell, K Ibbett, A Jones, T Moloney, M Prout, K Watkin, D |
| author_facet | Andrews, MD Brewster, A Crapnell, K Ibbett, A Jones, T Moloney, M Prout, K Watkin, D |
| author_sort | Andrews, MD |
| collection | OXFORD |
| description | Regioselective Dieckmann cyclisations using an N-acyloxazolidine derived from L-serine give substituted tetramic acids in high yield and enantioselectivity. The products are easily deprotected under mild conditions to give hydroxymethyltetramic acids. |
| first_indexed | 2024-03-06T21:14:39Z |
| format | Journal article |
| id | oxford-uuid:3f5a6f9a-f401-4af8-8e31-03208c041f0a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:14:39Z |
| publishDate | 1998 |
| record_format | dspace |
| spelling | oxford-uuid:3f5a6f9a-f401-4af8-8e31-03208c041f0a2022-03-26T14:31:28ZRegioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivativesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3f5a6f9a-f401-4af8-8e31-03208c041f0aEnglishSymplectic Elements at Oxford1998Andrews, MDBrewster, ACrapnell, KIbbett, AJones, TMoloney, MProut, KWatkin, DRegioselective Dieckmann cyclisations using an N-acyloxazolidine derived from L-serine give substituted tetramic acids in high yield and enantioselectivity. The products are easily deprotected under mild conditions to give hydroxymethyltetramic acids. |
| spellingShingle | Andrews, MD Brewster, A Crapnell, K Ibbett, A Jones, T Moloney, M Prout, K Watkin, D Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
| title | Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
| title_full | Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
| title_fullStr | Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
| title_full_unstemmed | Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
| title_short | Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
| title_sort | regioselective dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives |
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