UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

Hypoxia-inducible factor 1 (HIF-1) has been recognized as an important mediator of the reprogramming of carbohydrate metabolic pathways from oxidative phosphorylation to accelerated glycolysis. Although this reprogramming has been associated with the antioxidant and radioresistant properties of canc...

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Bibliographic Details
Main Authors: Nakashima, R, Goto, Y, Koyasu, S, Kobayashi, M, Morinibu, A, Yoshimura, M, Hiraoka, M, Hammond, E, Harada, H
Format: Journal article
Language:English
Published: Springer Nature 2017