Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro.

Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro.

Ghrelin, the recently identified hormone with GH-secreting and appetite-inducing effects, acts on the GH secretagogue receptor (GHS-R). GHS-R belongs to the G protein-coupled 7 transmembrane domain receptors and activates the phospholipase C pathway; it then leads to the release of GH from somatotro...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Orkin, R, New, D, Norman, D, Chew, S, Clark, A, Grossman, AB, Korbonits, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2003

Documenti analoghi

Mutational analysis of ghrelin and the growth hormone secretagogue receptor
di: Gueorguiev, M, et al.
Pubblicazione: (2004)

The growth hormone secretagogue hexarelin stimulates the hypothalamo-pituitary-adrenal axis via arginine vasopressin.
di: Korbonits, M, et al.
Pubblicazione: (1999)

The growth hormone secretagogue receptor.
di: Korbonits, M, et al.
Pubblicazione: (1999)

The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors.
di: Korbonits, M, et al.
Pubblicazione: (2001)

A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature.
di: Gueorguiev, M, et al.
Pubblicazione: (2009)

Hexarelin as a test of pituitary reserve in patients with pituitary disease.
di: Korbonits, M, et al.
Pubblicazione: (1999)

Ghrelin: update on a novel hormonal system.
di: Korbonits, M, et al.
Pubblicazione: (2004)

Ghrelin--a hormone with multiple functions.
di: Korbonits, M, et al.
Pubblicazione: (2004)

Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism.
di: Lim, C, et al.
Pubblicazione: (2013)

Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism
di: Lim, C, et al.
Pubblicazione: (2013)

Presence of ghrelin in normal and adenomatous human pituitary.
di: Korbonits, M, et al.
Pubblicazione: (2001)

Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors.
di: Korbonits, M, et al.
Pubblicazione: (1998)

Ghrelin's role as a major regulator of appetite and its other functions in neuroendocrinology.
di: Lim, C, et al.
Pubblicazione: (2010)

The effect of growth hormone secretagogues and neuropeptide Y on hypothalamic hormone release from acute rat hypothalamic explants.
di: Korbonits, M, et al.
Pubblicazione: (1999)

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.
di: Gueorguiev, M, et al.
Pubblicazione: (2009)

The expression of ghrelin O-acyltransferase (GOAT) in human tissues.
di: Lim, C, et al.
Pubblicazione: (2011)

The expression of ghrelin O-acyltransferase (GOAT) in human tissues
di: Lim, C, et al.
Pubblicazione: (2011)

The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes.
di: Garcia, E, et al.
Pubblicazione: (2009)

Neuroprotective actions of ghrelin and growth hormone secretagogues
di: Laura M. Frago, et al.
Pubblicazione: (2011-09-01)

The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.
di: Gnanapavan, S, et al.
Pubblicazione: (2002)

Akting and cycling: a tale of the pituitary.
di: Grossman, AB, et al.
Pubblicazione: (2004)

Growth hormone-releasing peptides (GHRP) and their analogues
di: Korbonits, M, et al.
Pubblicazione: (1996)

[Growth hormone-releasing peptides (GHRP) and their analogues]
di: Korbonits, M, et al.
Pubblicazione: (1996)

Growth hormone-releasing peptide and its analogues Novel stimuli to growth hormone release.
di: Korbonits, M, et al.
Pubblicazione: (1995)

Mutation in the ghrelin gene associated with increase in body weight and reduction of insulin secretion in tall, obese children
di: Gueorguiev, M, et al.
Pubblicazione: (2002)

The potential role of D(2) dopamine receptors as a target in the management of neuroendocrine tumors.
di: Ribeiro-Oliveira, A, et al.
Pubblicazione: (2008)

Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.
di: Nanzer, A, et al.
Pubblicazione: (2004)

Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin.
di: Mozid, A, et al.
Pubblicazione: (2003)

A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children.
di: Korbonits, M, et al.
Pubblicazione: (2002)

Development and Characterization of an F-labeled Ghrelin Peptidomimetic for Imaging the Cardiac Growth Hormone Secretagogue Receptor
di: Ahmed Abbas MSc, et al.
Pubblicazione: (2018-11-01)

The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin
di: Yuan Zhang, et al.
Pubblicazione: (2021-02-01)

Cyclins and their related proteins in pituitary tumourigenesis.
di: Muşat, M, et al.
Pubblicazione: (2010)

[Clinical value of neuropeptides GHRH and GHRP]
di: Savage, M, et al.
Pubblicazione: (1996)

Striant SR: a novel, effective and convenient testosterone therapy for male hypogonadism.
di: Korbonits, M, et al.
Pubblicazione: (2004)

The role of AMP-activated protein kinase in obesity.
di: Kola, B, et al.
Pubblicazione: (2008)

The role of somatostatin analogues in the treatment of neuroendocrine tumours.
di: Grozinsky-Glasberg, S, et al.
Pubblicazione: (2008)

The effect of growth hormone secretagogues on the release of growth hormone-releasing hormone, somatostatin, vasopressin, and corticotrophin-releasing hormone from the rat hypothalamus in vitro
di: Korbonits, M, et al.
Pubblicazione: (1998)

Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
di: Witherington, J, et al.
Pubblicazione: (2008)

Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification.
di: Heightman, T, et al.
Pubblicazione: (2007)

Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase.
di: Kola, B, et al.
Pubblicazione: (2005)