Importance of the active site "canopy" residues in an O2-tolerant [NiFe]-hydrogenase

The active site of Hyd-1, an oxygen-tolerant membrane-bound [NiFe]-hydrogenase from Escherichia coli, contains four highly conserved residues that form a "canopy" above the bimetallic center, closest to the site at which exogenous agents CO and O2 interact, substrate H2 binds, and a hydrid...

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Bibliographic Details
Main Authors: Brooke, E, Evans, R, Islam, S, Roberts, G, Wehlin, S, Carr, S, Phillips, S, Armstrong, F
Format: Journal article
Language:English
Published: American Chemical Society 2016