Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization.

Molecular dynamics simulations are used to model proteins that diffuse to DNA, bind, and dissociate; in the absence of any explicit interaction between proteins, or between templates, binding spontaneously induces local DNA compaction and protein aggregation. Small bivalent proteins form into rows [...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Brackley, C, Taylor, S, Papantonis, A, Cook, P, Marenduzzo, D
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2013