Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization.

Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization.

Molecular dynamics simulations are used to model proteins that diffuse to DNA, bind, and dissociate; in the absence of any explicit interaction between proteins, or between templates, binding spontaneously induces local DNA compaction and protein aggregation. Small bivalent proteins form into rows [...

書誌詳細
主要な著者:	Brackley, C, Taylor, S, Papantonis, A, Cook, P, Marenduzzo, D
フォーマット:	Journal article
言語:	English
出版事項:	2013

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