Investigating the role of RAD51 phosphorylation during the cell cycle

<p>The RAD51 recombinase safeguards genomic integrity by promoting double-strand break repair and replication fork protection. PLK1-dependent RAD51 phosphorylation contributes to RAD51 recruitment at DNA double strand breaks and stalled replication forks. During an unperturbed cell cycle, R...

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Bibliographic Details
Main Author: Wassing, I
Other Authors: Esashi, F
Format: Thesis
Language:English
Published: 2018