Biochemical rationale for transfusion of high titre COVID-19 convalescent plasma

We aimed to model binding of donor antibodies to virus that infects COVID-19 patients following transfusion of convalescent plasma (CCP). An immunosorbent assay was developed to determine apparent affinity (Kd, app). Antibody binding to virus was modelled using antibody concentration and estimations...

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Bibliographic Details
Main Authors: Verbrugghe, C, Wouters, E, Devloo, R, Nurmi, V, Seghers, S, De Bleser, D, Harvala, H, Compernolle, V, Feys, HB
Format: Journal article
Language:English
Published: Nature Research 2024