IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.

The realization that alterations in inhibitor of apoptosis (IAP) proteins are found in many types of human cancer and are associated with chemoresistance, disease progression and poor prognosis, has sparked a worldwide frenzy in the development of small pharmacological inhibitors of IAPs. The develo...

詳細記述

書誌詳細
主要な著者: Gyrd-Hansen, M, Meier, P
フォーマット: Journal article
言語:English
出版事項: 2010