Very large treatment effects in randomised trials as an empirical marker to indicate whether subsequent trials are necessary: meta-epidemiological assessment

<strong>Objective:</strong> Most healthcare interventions provide modest benefits, but occasionally trials report very large improvements over existing treatments or inactive controls. This often leads to speculation that further trials may be unnecessary. We examined whether a very larg...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Nagendran, M, Pereira, T, Kiew, G, Altman, D, Maruthappu, M, Ioannidis, J, McCulloch, P
Format: Journal article
Sprache:English
Veröffentlicht: BMJ Publishing Group 2016