Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis.

BACKGROUND: Multiple sclerosis results from T-cell-dependent inflammatory demyelination of the central nervous system. Our objective was long-term suppression of inflammation with short-term monoclonal antibody treatment. METHODS: We depleted 95% of circulating lymphocytes in 27 patients with multi...

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Hlavní autoři: Coles, A, Wing, M, Smith, S, Coraddu, F, Greer, S, Taylor, C, Weetman, A, Hale, G, Chatterjee, V, Waldmann, H, Compston, A
Médium: Journal article
Jazyk:English
Vydáno: 1999