Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore.
Nanopores are under investigation for single-molecule DNA sequencing. The alpha-hemolysin (alphaHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual immobilized ssDNA molecules. We have modified the recognition point R(1) by extensive mutagenesis...
Main Authors: | , , , , , |
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Formato: | Journal article |
Idioma: | English |
Publicado: |
2010
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