Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore.
Nanopores are under investigation for single-molecule DNA sequencing. The alpha-hemolysin (alphaHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual immobilized ssDNA molecules. We have modified the recognition point R(1) by extensive mutagenesis...
Príomhchruthaitheoirí: | Stoddart, D, Heron, A, Klingelhoefer, J, Mikhailova, E, Maglia, G, Bayley, H |
---|---|
Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2010
|
Míreanna comhchosúla
Míreanna comhchosúla
-
Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge.
de réir: Maglia, G, et al.
Foilsithe / Cruthaithe: (2008) -
Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore.
de réir: Franceschini, L, et al.
Foilsithe / Cruthaithe: (2012) -
Fluorinated amphiphiles control the insertion of α-hemolysin pores into lipid bilayers.
de réir: Raychaudhuri, P, et al.
Foilsithe / Cruthaithe: (2011) -
Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore.
de réir: Japrung, D, et al.
Foilsithe / Cruthaithe: (2010) -
Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
de réir: Song, L, et al.
Foilsithe / Cruthaithe: (1996)