Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore.

Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore.

Nanopores are under investigation for single-molecule DNA sequencing. The alpha-hemolysin (alphaHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual immobilized ssDNA molecules. We have modified the recognition point R(1) by extensive mutagenesis...

Bibliografske podrobnosti
Main Authors:	Stoddart, D, Heron, A, Klingelhoefer, J, Mikhailova, E, Maglia, G, Bayley, H
Format:	Journal article
Jezik:	English
Izdano:	2010

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