Enantioselective alkylative double ring opening of epoxides: synthesis of enantioenriched unsaturated diols and amino alcohols.
Enantioselective generation and intermolecular trapping of a lithium carbenoid occurs in the reaction of epoxides of 2,5-dihydrofuran, 2,5-dihydropyrrole, and oxa- and aza-bicyclo[n.2.1]alkenes (n = 2, 3) with organolithium compounds in the presence of external chiral ligands. This methodology leads...
| Автори: | , , , , , , , |
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| Формат: | Journal article |
| Мова: | English |
| Опубліковано: |
2002
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