Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

Cross-reactive immune responses to SARS-CoV-2 have been observed in pre-pandemic cohorts and proposed to contribute to host protection. Here we assess 52 COVID-19 household contacts to capture immune responses at the earliest timepoints after SARS-CoV-2 exposure. Using a dual cytokine FLISpot assay...

Full description

Bibliographic Details
Main Authors: Kundu, R, Narean, JS, Wang, L, Fenn, J, Pillay, T, Fernandez, ND, Conibear, E, Koycheva, A, Davies, M, Tolosa-Wright, M, Hakki, S, Varro, R, McDermott, E, Hammett, S, Cutajar, J, Thwaites, RS, Parker, E, Rosadas, C, McClure, M, Tedder, R, Taylor, GP, Dunning, J, Lalvani, A
Format: Journal article
Language:English
Published: Springer Nature 2022