Donor age significantly influences the Raman spectroscopic biomolecular fingerprint of human pancreatic extracellular matrix proteins following collagenase-based digestion

<p>Despite the enormous advances in the field of clinical pancreatic islet transplantation over the past two decades, the human islet isolation procedure remains suboptimal. Islets are extracted (isolated) from the exocrine tissue of donor pancreases using neutral protease (NP) and collagenase...

Full description

Bibliographic Details
Main Authors: Spiers, RM, Marzi, J, Brauchle, EM, Cross, SE, Vaughan, RH, Bateman, PA, Hughes, SJ, Schenke-Layland, K, Johnson, PRV
Format: Journal article
Language:English
Published: Elsevier 2019