Modification of K-ATP channels in pancreatic beta-cells by trypsin.
The inside-out configuration of the patch-clamp method was used to study the effects of trypsin on the activity of ATP-sensitive potassium (K-ATP) channels from isolated mouse pancreatic beta-cells. Trypsin (20 micrograms/ml) irreversibly enhanced channel activity around twofold by reducing the inte...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1993
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