Modification of K-ATP channels in pancreatic beta-cells by trypsin.

The inside-out configuration of the patch-clamp method was used to study the effects of trypsin on the activity of ATP-sensitive potassium (K-ATP) channels from isolated mouse pancreatic beta-cells. Trypsin (20 micrograms/ml) irreversibly enhanced channel activity around twofold by reducing the inte...

Полное описание

Библиографические подробности
Главные авторы: Proks, P, Ashcroft, F
Формат: Journal article
Язык:English
Опубликовано: 1993