Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study.

OBJECTIVE: The efficacy and safety of adding liraglutide (a glucagon-like peptide-1 receptor agonist) to metformin were compared with addition of placebo or glimepiride to metformin in subjects previously treated with oral antidiabetes (OAD) therapy. RESEARCH DESIGN AND METHODS: In this 26-week, do...

Full description

Bibliographic Details
Main Authors: Nauck, M, Frid, A, Hermansen, K, Shah, N, Tankova, T, Mitha, I, Zdravkovic, M, Düring, M, Matthews, DR
Format: Conference item
Published: 2009