Mechanosensing in T lymphocyte activation.
Mechanical forces play an increasingly recognized role in modulating cell function. This report demonstrates mechanosensing by T cells, using polyacrylamide gels presenting ligands to CD3 and CD28. Naive CD4 T cells exhibited stronger activation, as measured by attachment and secretion of IL-2, with...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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