Alpha-synuclein proximity ligation assay (AS-PLA) in brain sections to probe for alpha-synuclein oligomers
Alpha-synuclein oligomers are thought to be toxic mediators of Parkinson’s disease and other alpha-synucleinopathies, but their histological detection in situ in diseased brain has been a challenge in the field for some time. Here we describe a method, the alpha-synuclein proximity ligation assay (A...
| Main Authors: | , , |
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| Format: | Book section |
| Language: | English |
| Published: |
Springer
2019
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