Loss of PFKFB4 induces cell death in mitotically arrested ovarian cancer cells

Taxanes represent some of the most commonly used chemotherapeutic agents for ovarian cancer treatment. However, they are only effective in approximately 40% of patients. Novel therapeutic strategies are required to potentiate their effect and improve patient outcome. A hallmark of many cancers is th...

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Bibliographic Details
Main Authors: Taylor, C, Mannion, D, Miranda, F, Karaminejadranjbar, M, Herrero-Gonzalez, S, Hellner, K, Zheng, Y, Bartholomeusz, G, Bast, R, Ahmed, A
Format: Journal article
Language:English
Published: Impact Journals 2017