Immunogen design to focus the B-cell repertoire.
PURPOSE OF REVIEW: This review aims to bring together recent developments relevant to the design of HIV-1 envelope glycoprotein-based immunogens to elicit broadly neutralizing antibodies (bNAbs). RECENT FINDINGS: The combined use of structural biology and deep sequencing of antigen-specific B-cell l...
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Format: | Journal article |
Language: | English |
Published: |
2014
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