Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

DNA methylation is an important epigenetic modification that is known to be altered in rheumatoid arthritis synovial fibroblasts (RASF). Here, we compared the status of promoter DNA methylation of SF from patients with very early RA with SF from patients with resolving arthritis, fully established R...

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Bibliografiske detaljer
Main Authors: Karouzakis, E, Raza, K, Kolling, C, Buckley, C, Gay, S, Filer, A, Ospelt, K
Format: Journal article
Udgivet: Nature Publishing Group 2018

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