Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

DNA methylation is an important epigenetic modification that is known to be altered in rheumatoid arthritis synovial fibroblasts (RASF). Here, we compared the status of promoter DNA methylation of SF from patients with very early RA with SF from patients with resolving arthritis, fully established R...

Detaylı Bibliyografya
Asıl Yazarlar:	Karouzakis, E, Raza, K, Kolling, C, Buckley, C, Gay, S, Filer, A, Ospelt, K
Materyal Türü:	Journal article
Baskı/Yayın Bilgisi:	Nature Publishing Group 2018

Benzer Materyaller

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis
Yazar:: Emmanuel Karouzakis, ve diğerleri
Baskı/Yayın Bilgisi: (2018-05-01)

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
Yazar:: Frank-Bertoncelj, M, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
Yazar:: Mojca Frank-Bertoncelj, ve diğerleri
Baskı/Yayın Bilgisi: (2017-03-01)

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts
Yazar:: Pearson, MJ, ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Genomic responses of mouse synovial fibroblasts during tumor necrosis factor-driven arthritogenesis greatly mimic those in human rheumatoid arthritis
Yazar:: Ntougkos, E, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Differential effect of lactate on synovial fibroblast and macrophage effector functions
Yazar:: Pucino, V, ve diğerleri
Baskı/Yayın Bilgisi: (2023)

Location, location, location: how the tissue microenvironment affects inflammation in RA
Yazar:: Buckley, CD, ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Differential effect of lactate on synovial fibroblast and macrophage effector functions
Yazar:: Valentina Pucino, ve diğerleri
Baskı/Yayın Bilgisi: (2023-05-01)

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
Yazar:: Montero-Melendez, T, ve diğerleri
Baskı/Yayın Bilgisi: (2020)

Natural killer cell and synovial fibroblast cross talk - A role in the pathogenesis of spondyloarthritis
Yazar:: Chan, A, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Notch signalling drives synovial fibroblast identity and arthritis pathology
Yazar:: Wei, K, ve diğerleri
Baskı/Yayın Bilgisi: (2020)

Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts
Yazar:: Crowley, T, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
Yazar:: Xiangyu Ge, ve diğerleri
Baskı/Yayın Bilgisi: (2021-08-01)

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
Yazar:: Trinidad Montero-Melendez, ve diğerleri
Baskı/Yayın Bilgisi: (2020-02-01)

A proinflammatory response is mediated by synovial fibroblast and natural killer cell interaction in rheumatoid arthritis and spondyloarthritis
Yazar:: Chan, A, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Bromodomain Protein Inhibitors Reorganize the Chromatin of Synovial Fibroblasts
Yazar:: Monika Krošel, ve diğerleri
Baskı/Yayın Bilgisi: (2023-04-01)

IL-15 expression on RA synovial fibroblasts promotes B cell survival.
Yazar:: Marta Benito-Miguel, ve diğerleri
Baskı/Yayın Bilgisi: (2012-01-01)

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a proinflammatory phenotype in Rheumatoid Arthritis
Yazar:: Wang, Y, ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Allele-specific protein binding within the CD40 locus in human synovial fibroblasts and immune cells
Yazar:: Caroline Ospelt, ve diğerleri
Baskı/Yayın Bilgisi: (2023-10-01)

Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage
Yazar:: Croft, AP, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts
Yazar:: Marietta Armaka, ve diğerleri
Baskı/Yayın Bilgisi: (2018-02-01)

TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles
Yazar:: Mojca Frank-Bertoncelj, ve diğerleri
Baskı/Yayın Bilgisi: (2018-01-01)

Ultrasound-detected synovitis and tenosynovitis predict RA in early disease
Yazar:: Sahbudin, I, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

BRD3 Regulates the Inflammatory and Stress Response in Rheumatoid Arthritis Synovial Fibroblasts
Yazar:: Tanja Seifritz, ve diğerleri
Baskı/Yayın Bilgisi: (2023-11-01)

STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function
Yazar:: Megan M. Hanlon, ve diğerleri
Baskı/Yayın Bilgisi: (2019-08-01)

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis
Yazar:: Choi, I, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis
Yazar:: Yilin Wang, ve diğerleri
Baskı/Yayın Bilgisi: (2021-04-01)

Nomenclature clarification: synovial fibroblasts and synovial mesenchymal stem cells
Yazar:: Fangqi Li, ve diğerleri
Baskı/Yayın Bilgisi: (2019-08-01)

Identification of a transitional fibroblast functional phenotype in very early rheumatoid arthritis
Yazar:: Filer, A, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

THE PRODUCTION OF PRO- AND ANTIINFLAMMATORY CYTOKINES BY SYNOVIAL FIBROBLASTS OF PATIENTS WITH RHEUMATOID ARTHRITIS IN VITRO WHEN USING DNA METHYLATION MODULATORS - INVESTIGATIVE STUDY
Yazar:: M. A. Shnayder, ve diğerleri
Baskı/Yayın Bilgisi: (2019-05-01)

Reprogramming of synovial macrophage metabolism by synovial fibroblasts under inflammatory conditions
Yazar:: Noritaka Saeki, ve diğerleri
Baskı/Yayın Bilgisi: (2020-11-01)

Fibroblasts as therapeutic targets in rheumatoid arthritis and cancer
Yazar:: Maria Juarez, ve diğerleri
Baskı/Yayın Bilgisi: (2012-02-01)

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels
Yazar:: Monika Krošel, ve diğerleri
Baskı/Yayın Bilgisi: (2023-10-01)

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts
Yazar:: Friščić, J, ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
Yazar:: Aungier, S, ve diğerleri
Baskı/Yayın Bilgisi: (2018)

New Developments in Transcriptomic Analysis of Synovial Tissue
Yazar:: Hayley L. Carr, ve diğerleri
Baskı/Yayın Bilgisi: (2020-01-01)

The role of rank ligand in RA synovial macrophage-osteoclast differentiation
Yazar:: Itonaga, I, ve diğerleri
Baskı/Yayın Bilgisi: (2000)

Decrease in articular hypoxia and synovial blood flow at early time points following infliximab and etanercept treatment in rheumatoid arthritis
Yazar:: Fisher, B, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Multiomics landscape of synovial fibroblasts in rheumatoid arthritis
Yazar:: Haruka Tsuchiya, ve diğerleri
Baskı/Yayın Bilgisi: (2021-03-01)

Effective extraction of Xuetongsu and its role in preventing RA synovial hyperplasia by targeting synovial cell migration and apoptosis
Yazar:: Yasi Deng, ve diğerleri
Baskı/Yayın Bilgisi: (2024-10-01)