Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy

<p><strong>Introduction:</strong> Hypertrophic cardiomyopathy (HCM) is a leading cause of lethal arrhythmias in the young. Although the arrhythmic substrate has been hypothesised to be amenable to late Na+ block with ranolazine, the specific mechanisms are not fully understood. The...

Полное описание

Библиографические подробности
Главные авторы: Coleman, JA, Doste, R, Beltrami, M, Argirò, A, Coppini, R, Olivotto, I, Raman, B, Bueno Orovio, A
Формат: Journal article
Язык:English
Опубликовано: Frontiers Media 2024