Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy

<p><strong>Introduction:</strong> Hypertrophic cardiomyopathy (HCM) is a leading cause of lethal arrhythmias in the young. Although the arrhythmic substrate has been hypothesised to be amenable to late Na+ block with ranolazine, the specific mechanisms are not fully understood. The...

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Main Authors: Coleman, JA, Doste, R, Beltrami, M, Argirò, A, Coppini, R, Olivotto, I, Raman, B, Bueno Orovio, A
格式: Journal article
语言:English
出版: Frontiers Media 2024