Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

<div> <h3>Background</h3> <p>The insulin-degrading enzyme gene (<em>IDE</em>) is a strong functional and positional candidate for late onset Alzheimer's disease (LOAD).</p> </div> <div> <h3>Methodology/Principal Findings</h3> <...

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Main Authors: Belbin, O, Zou, F, Allen, M, Ertekin-Taner, N, Ansari, M, Wilcox, S, Kashino, MR, Ma, L, Younkin, L, Younkin, S, Younkin, C, Dincman, T, Howard, M, Howell, C, Stanton, C, Watson, C, Crump, M, Vitart, V, Hayward, C, Hastie, N, Rudan, I, Campbell, H, Polasek, O, Brown, K, Passmore, P, Craig, D, McGuinness, B, Todd, S, Kehoe, P, Mann, D, Smith, A, Beaumont, H, Warden, D, Holmes, C, Heun, R, Kölsch, H, Kalsheker, N, Pankratz, V, Dickson, D, Graff-Radford, N, Petersen, R, Wright, A, Morgan, K
Format: Journal article
Jezik:English
Izdano: Public Library of Science 2010