Characterisation of 2-oxoglutarate- and fe(II)-dependent oxygenases targeting the protein synthesis apparatus

Characterisation of 2-oxoglutarate- and fe(II)-dependent oxygenases targeting the protein synthesis apparatus

<p>Members of the 2-oxoglutarate (2OG)- and Fe(II)-dependent oxygenase (2OG oxygenase) superfamily catalyse a wide range of oxidative reactions in biology. 2OG oxygenases require Fe(II) and atmospheric oxygen for their activity, and couple substrate oxidation with the decarboxylation of 2OG in...

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Manylion Llyfryddiaeth
Prif Awdur:	Feng, T
Awduron Eraill:	Ratcliffe, P
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2014
Pynciau:	Cell Biology Biochemistry

Eitemau Tebyg

Kinetic and mechanistic studies of oxygen sensing Fe(II)/2-oxoglutarate dependent oxygenases
gan: Tarhonskaya, H
Cyhoeddwyd: (2014)

NMR studies on 2-oxoglutarate oxygenases
gan: Leung, IKH
Cyhoeddwyd: (2013)

Crystallographic studies on 2-oxoglutarate dependent oxygenases
gan: Aik, WS
Cyhoeddwyd: (2014)

Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases
gan: Thalhammer, A
Cyhoeddwyd: (2012)

2-oxoglutarate-dependent oxygenases
gan: Islam, M, et al.
Cyhoeddwyd: (2018)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
gan: Szollossi, A
Cyhoeddwyd: (2012)

Interplay between 2-oxoglutarate oxygenases and cancer: studies on the aspartyl/asparaginyl-beta-hydroxylase
gan: Pfeffer, I
Cyhoeddwyd: (2014)

Identification of inhibitors for a family of human oxoglutarate-dependent oxygenases
gan: Nowak, R
Cyhoeddwyd: (2015)

Structural characterisation of calnexin cycle components and assessment as antiviral targets
gan: Hill, J
Cyhoeddwyd: (2018)

Inhibition of 2-oxoglutarate dependent oxygenases.
gan: Rose, N, et al.
Cyhoeddwyd: (2011)

Structural and biochemical characterisation of human integral membrane proteins regarded as potential therapeutic targets
gan: da Costa Cabral Gomes Páscoa, T
Cyhoeddwyd: (2022)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
gan: Schofield, C, et al.
Cyhoeddwyd: (1999)

Dynamic combinatorial mass spectrometry for 2-oxoglutarate oxygenase inhibition
gan: Demetriades, M
Cyhoeddwyd: (2013)

Bi-directional regulation of type I interferon signaling by heme oxygenase-1
gan: Miaomiao Wu, et al.
Cyhoeddwyd: (2024-03-01)

Structural studies on human 2-oxoglutarate dependent oxygenases.
gan: McDonough, M, et al.
Cyhoeddwyd: (2010)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
gan: Mantri, M, et al.
Cyhoeddwyd: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
gan: Mantri, M, et al.
Cyhoeddwyd: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases.
gan: Mantri, M, et al.
Cyhoeddwyd: (2012)

Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling
gan: Abigail Brewer, et al.
Cyhoeddwyd: (2024-08-01)

Identification and characterisation of alternative forms of SETD2/HYPB (SET domain-containing protein 2 / Huntingtin yeast partner B)
gan: Lee, BM
Cyhoeddwyd: (2011)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
gan: Zayer, A
Cyhoeddwyd: (2012)

A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases.
gan: McNeill, L, et al.
Cyhoeddwyd: (2005)

Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca2+ channel function to control glucose dependent insulin secretion
gan: Hallahan, N, et al.
Cyhoeddwyd: (2021)

The nucleolus functions as the compartment for histone H2B protein degradation
gan: Yanping Liu, et al.
Cyhoeddwyd: (2021-04-01)

Roles of oxygenases in nucleic acid modification
gan: Bagg, E
Cyhoeddwyd: (2011)

Role of structural dynamics in selectivity and mechanism of non-heme Fe(II) and 2-oxoglutarate-dependent oxygenases involved in DNA repair
gan: Waheed, SO, et al.
Cyhoeddwyd: (2020)

Role of Structural Dynamics in Selectivity and Mechanism of Non-heme Fe(II) and 2‑Oxoglutarate-Dependent Oxygenases Involved in DNA Repair
gan: Sodiq O. Waheed, et al.
Cyhoeddwyd: (2020-05-01)

iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells
gan: Habib Bouguenina, et al.
Cyhoeddwyd: (2023-07-01)

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes.
gan: Schofield, C, et al.
Cyhoeddwyd: (1999)

Exploring links between 2-oxoglutarate-dependent oxygenases and Alzheimer's disease
gan: Liu, H, et al.
Cyhoeddwyd: (2022)

Protein phosphatase 6 function and regulation throughout the cell cycle
gan: Ahel, J
Cyhoeddwyd: (2018)

In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies
gan: Nancy E. Sealover, et al.
Cyhoeddwyd: (2024-01-01)

Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway
gan: Justin B. Davis, et al.
Cyhoeddwyd: (2018-05-01)

Novel inverse agonists for the orphan G protein-coupled receptor 6
gan: Alyssa S. Laun, et al.
Cyhoeddwyd: (2018-11-01)

The role of iron and 2-oxoglutarate oxygenases in signalling.
gan: Hewitson, K, et al.
Cyhoeddwyd: (2003)

Expanding chemical biology of 2-oxoglutarate oxygenases.
gan: Loenarz, C, et al.
Cyhoeddwyd: (2008)

Role of mutual information for predicting contact residues in proteins
gan: Gomes, M
Cyhoeddwyd: (2012)

Mechanisms of TonB-dependent protein import in Pseudomonas aeruginosa
gan: Goult, J
Cyhoeddwyd: (2021)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
gan: Thalhammer, A, et al.
Cyhoeddwyd: (2012)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
gan: Thalhammer, A, et al.
Cyhoeddwyd: (2012)