Orchestration of the spindle assembly checkpoint by CDK1‐cyclin B1

In mitosis, the spindle assembly checkpoint (SAC) monitors the formation of microtubule‐kinetochore attachments during capture of chromosomes by the mitotic spindle. Spindle assembly is complete once there are no longer any unattached kinetochores. Here, we will discuss the mechanism and key compone...

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Bibliographic Details
Main Authors: Hayward, D, Alfonso-Pérez, T, Gruneberg, U
Format: Journal article
Language:English
Published: Wiley 2019