A point mutation in CD45 may be associated with an increased risk of HIV-1 infection.

A point mutation in CD45 may be associated with an increased risk of HIV-1 infection.

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The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Here we show that abnormal CD45 splicing caused by a C77G transversion in exon A of the gene encoding CD45 (...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Tchilian, E, Wallace, D, Dawes, R, Imami, N, Burton, C, Gotch, F, Beverley, P
פורמט: Journal article
שפה:English
יצא לאור: 2001

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