A point mutation in CD45 may be associated with an increased risk of HIV-1 infection.

The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Here we show that abnormal CD45 splicing caused by a C77G transversion in exon A of the gene encoding CD45 (...

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Xehetasun bibliografikoak
Egile Nagusiak: Tchilian, E, Wallace, D, Dawes, R, Imami, N, Burton, C, Gotch, F, Beverley, P
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2001