Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.

UNLABELLED: Human leukocyte antigen B27 (HLA-B27) is associated with protection in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. This protective role is linked to single immunodominant HLA-B27-restricted CD8+ T-cell epitopes in both infections. In order to define the rela...

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Bibliographic Details
Main Authors:	Neumann-Haefelin, C, Timm, J, Schmidt, J, Kersting, N, Fitzmaurice, K, Oniangue-Ndza, C, Kemper, M, Humphreys, I, McKiernan, S, Kelleher, D, Lohmann, V, Bowness, P, Huzly, D, Rosen, H, Kim, A, Lauer, G, Allen, T, Barnes, E, Roggendorf, M, Blum, H, Thimme, R
Format:	Journal article
Language:	English
Published:	2010

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.

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