Structural knowledge or X-ray damage? A case study on xylose isomerase illustrating both

Xylose isomerase (XI) is an industrially important metalloprotein studied for decades. Its reaction mechanism has been postulated to involve movement of the catalytic metal cofactor to several different conformations. Here, a dose-dependent approach was used to investigate the radiation damage effec...

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Bibliographic Details
Main Authors: Taberman, H, Bury, C, Van Der Woerd, M, Snell, E, Garman, E
Format: Journal article
Published: International Union of Crystallography 2019