PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression

<p><strong>Introduction:</strong> Clinical depression is usually treated in primary care with psychological therapies and antidepressant medication. However, when patients do not respond to at least two or more antidepressants within a depressive episode, they are considered to hav...

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Main Authors: Au-Yeung, S, Griffiths, J, Roberts, S, Edwards, C, Bogacz, R, Attenburrow, M-J, Watson, S, Cleare, A, Harmer, C, Kessler, D, Yu, L-M, Chan, F, Cipriani, A, Rendell, J, Evans, J, Lewis, G, Singh, I, Simon, J, Harrison, P, Cowen, P, Shanyinde, M, Geddes, J, Browning, M
Format: Journal article
Language:English
Published: BMJ Publishing Group 2021