Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

Thousands of genetic variants have been identified, which contribute to the development of complex diseases, but determining how to elucidate their biological consequences for translation into clinical benefit is challenging. Conflicting evidence regarding the functional impact of genetic variants i...

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Prif Awduron: Dendrou, C, Cortes, A, Shipman, L, Evans, H, Attfield, K, Jostins, L, Barber, T, Kaur, G, Balaram Kuttikkatte, S, Leach, O, Desel, C, Faergeman, S, Cheeseman, J, Neville, M, Bell, J, Karpe, F, McVean, G, Fugger, L
Fformat: Journal article
Iaith:English
Cyhoeddwyd: American Association for the Advancement of Science 2016

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