Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes.

A primary motivation for sequencing the mouse genome was to accelerate the discovery of mammalian genes by using sequence conservation between mouse and human to identify coding exons. Achieving this goal proved challenging because of the large proportion of the mouse and human genomes that is appar...

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Bibliographic Details
Main Authors: Guigo, R, Dermitzakis, E, Agarwal, P, Ponting, C, Parra, G, Reymond, A, Abril, J, Keibler, E, Lyle, R, Ucla, C, Antonarakis, SE, Brent, MR
Format: Journal article
Language:English
Published: 2003