Intracellular pH and the stimulus-secretion coupling in insulin-producing RINm5F cells.

The regulation of intracellular pH (pHi) and its role in the insulin-secretory process were evaluated, by using the clonal insulin-secreting cell line RINm5F. Glyceraldehyde, lactate and dihydroxyacetone decreased pHi, but only the first two released insulin. In the presence of extracellular Na+ the...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Juntti-Berggren, L, Rorsman, P, Siffert, W, Berggren, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1992