Modelling acidosis and the cell cycle in multicellular tumour spheroids

Modelling acidosis and the cell cycle in multicellular tumour spheroids

A partial differential equation model is developed to understand the effect that nutrient and acidosis have on the distribution of proliferating and quiescent cells and dead cell material (necrotic and apoptotic) within a multicellular tumour spheroid. The rates of cell quiescence and necrosis depen...

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Dettagli Bibliografici
Autori principali:	Tindall, M, Dyson, L, Smallbone, K, Maini, P
Natura:	Journal article
Pubblicazione:	Elsevier 2012

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