Modelling acidosis and the cell cycle in multicellular tumour spheroids

A partial differential equation model is developed to understand the effect that nutrient and acidosis have on the distribution of proliferating and quiescent cells and dead cell material (necrotic and apoptotic) within a multicellular tumour spheroid. The rates of cell quiescence and necrosis depen...

Descripció completa

Dades bibliogràfiques
Autors principals: Tindall, M, Dyson, L, Smallbone, K, Maini, P
Format: Journal article
Publicat: Elsevier 2012