MPS1 localizes to end-on microtubule-attached kinetochores to promote microtubule release

In eukaryotes, the spindle assembly checkpoint protects genome stability in mitosis by preventing chromosome segregation until incorrect microtubule-kinetochore attachment geometries have been eliminated and chromosome biorientation has been completed. These error correction and checkpoint processes...

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Bibliographic Details
Main Authors: Hayward, D, Roberts, E, Gruneberg, U
Format: Journal article
Language:English
Published: Cell Press 2022