Use of patient-derived cellular models to investigate the mechanistic basis of circadian dysfunctions and chronomodulatory drugs in bipolar disorder
<p>Bipolar disorder is a highly incapacitating neuropsychiatric disorder, where patients exhibit cycling episodes of mania and depression. In addition to these characteristics, sleep and circadian rhythm disruptions are frequently observed through changes in physiology and behaviour. Lithium t...
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| Format: | Thesis |
| Language: | English |
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2018
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