Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.

BACKGROUND: N-glycosylation occurs in the variable region of about 10% of antibodies but the role of carbohydrate at this location is still poorly understood. OBJECTIVES: We investigated the function of N-glycosylation in the variable region of the heavy chain of a human monoclonal antibody, mAb-LE2...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Jacquemin, M, Radcliffe, C, Lavend'homme, R, Wormald, M, Vanderelst, L, Wallays, G, Dewaele, J, Collen, D, Vermylen, J, Dwek, R, Saint-Remy, J, Rudd, P, Dewerchin, M
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2006