A scalable variational inference approach for increased mixed-model association power

The rapid growth of modern biobanks is creating new opportunities for large-scale genome-wide association studies (GWASs) and the analysis of complex traits. However, performing GWASs on millions of samples often leads to trade-offs between computational efficiency and statistical power, reducing th...

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Main Authors: Loya, H, Kalantzis, G, Cooper, F, Palamara, PF
פורמט: Journal article
שפה:English
יצא לאור: Nature Research 2025