Investigating interactions of the pentraxins serum amyloid P component and C-reactive protein by mass spectrometry.

The oligomeric state of human SAP (serum amyloid P component) in the absence and presence of known ligands has been investigated using nanoelectrospray ionization MS. At pH 8.0, in the absence of Ca2+, SAP has been shown to consist of pentameric and decameric forms. In the presence of physiological...

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Autori principali: Aquilina, J, Robinson, C
Natura: Journal article
Lingua:English
Pubblicazione: 2003