The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.

OBJECTIVE: To test whether ETS-related gene (Erg) inhibits tumor necrosis factor (TNF)-α-dependent endothelial activation and inflammation. METHODS AND RESULTS: Endothelial activation underlies many vascular diseases, including atherosclerosis. Endothelial activation by proinflammatory cytokines dec...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Sperone, A, Dryden, N, Birdsey, G, Madden, L, Johns, M, Evans, P, Mason, J, Haskard, DO, Boyle, J, Paleolog, E, Randi, A
Formaat: Journal article
Taal:English
Gepubliceerd in: 2011