Post-transcriptional control of IL-1 gene expression in the acute monocytic leukemia line THP-1.

The acute monocytic leukemia cell line THP-1 secretes predominantly IL-1 beta after treatment with bacterial lipopolysaccharide and tumour promoting phorbol ester (PMA). IL-1 alpha is also secreted, but represents less than 10% of the total IL-1 activity. This differential is reflected at the level...

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Autori principali: Turner, M, Chantry, D, Feldmann, M
Natura: Journal article
Lingua:English
Pubblicazione: 1988