Post-transcriptional control of IL-1 gene expression in the acute monocytic leukemia line THP-1.
The acute monocytic leukemia cell line THP-1 secretes predominantly IL-1 beta after treatment with bacterial lipopolysaccharide and tumour promoting phorbol ester (PMA). IL-1 alpha is also secreted, but represents less than 10% of the total IL-1 activity. This differential is reflected at the level...
Main Authors: | Turner, M, Chantry, D, Feldmann, M |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
1988
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