Studying the organization of DNA repair by single-cell and single-molecule imaging.

DNA repair safeguards the genome against a diversity of DNA damaging agents. Although the mechanisms of many repair proteins have been examined separately in vitro, far less is known about the coordinated function of the whole repair machinery in vivo. Furthermore, single-cell studies indicate that...

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Bibliografske podrobnosti
Main Authors: Uphoff, S, Kapanidis, A
Format: Journal article
Jezik:English
Izdano: 2014