Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy.

BACKGROUND: Hypertrophic cardiomyopathy patients exhibit myocardial energetic impairment, but a causative role for this energy deficiency in the pathophysiology of hypertrophic cardiomyopathy remains unproven. We hypothesized that the metabolic modulator perhexiline would ameliorate myocardial energ...

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Detalles Bibliográficos
Main Authors: Abozguia, K, Elliott, P, McKenna, W, Phan, T, Nallur-Shivu, G, Ahmed, I, Maher, A, Kaur, K, Taylor, J, Henning, A, Ashrafian, H, Watkins, H, Frenneaux, M
Formato: Journal article
Idioma:English
Publicado: 2010