Asymmetric synthesis of homochiral Baylis-Hillman products employing (R)-N-methyl-N-alpha-methylbenzyl amide

The conjugate addition of (R)-N-methyl-N-α-methylbenzyl amide to tert-butyl cinnamate followed by an asymmetric aldol reaction and subsequent N-oxidation/Cope elimination affords β-substituted homochiral Baylis-Hillman products in good yield. Copyright (C) 2000 Elsevier Science Ltd.

書誌詳細
主要な著者: Davies, S, Smethurst, C, Smith, A, Smyth, G
フォーマット: Journal article
言語:English
出版事項: 2000